Dedicated mainly to those who already have a minimal experience with a PC Flight Simulator, this book aims to guide the reader into the world of flights instrumentally controlled both by the autopilot and/or GPS.This booklet opens with light aircraft of general aviation (equipped with automatic navigation systems but) with traditional analogue instrumentation to move at first to propeller-driven aircraft with digital displays and more sophisticated instrumentation and secondly to jets with particular reference to the Learjet 45 and the Boeing 737 with some complete example of flights, all accompanied by many illustrations taken from the application itself.In closing, a Technical Appendix illustrates some types of aircraft engines based on piston and turbo principle of operation.