The book deals with the relationship among man's constructions, living internal environment, mental space and their links with psychological health and subjetive wellness.The study of residential wellness is treated trough the human-environment relationship analysis, which includes: the different dimension of life environment; the concept of space; the arrangement and organization of space; the definition of external and internal space; the possible correspondence between mental space and living internal environment. Philosophical, architectural, psysical-mathematical and medical (both neurological and psychiatric) perspectives are considered, regarding spatiality and concept of space. These contributions are proposed as a books and articles review, followed by a critical comment.Each chapter of the book has been illustrated by free download fotos, which help understanding theoretical aspects.