Secrecy, Competition, Misinformation, and Poor Coordination plague nearly every major public health crisis-and with the COVID-19 pandemic we are once again seeing their deadly consequences. When Ebola broke out across West Africa in 2014, Dr. Sheik Humarr Khan, a world-famous expert in viral hemorrhagic fever, worked under impossible conditions to save patients and their families until he was infected himself and died of the disease. Dr. Pardis Sabeti, who worked with Dr. Khan, and her Pulitzer Prize-winning collaborator Lara Salahi spoke with nurses, patients, and members of the international team fighting the outbreak to piece together what happened and why. A work of fearless integrity and unassailable authority, Outbreak Culture seeks to change the toxic culture governing global emergency responses, and ensure we make some urgently needed changes before the next pandemic.