Proceedings from the XVIIIth International Winter Meeting of the Swiss Society of Neuropathology, held in March 2000 in St. Moritz, Switzerland, bringing together neuropathologists, clinicians and neuroscientists interested in disease mechanisms. Nineteen contributions by over 60 international specialists explore a variety of dementing disorders. A sampling of topics: the molecular parameters of tau pathology; argyrophilic grain disease; the spectrum of vascular disease in dementia; ubiquitin and the molecular pathology of neurodegenerative diseases; and pathological mechanisms in polyglutamine expansion diseases. Annotation c. Book News, Inc., Portland, OR (booknews.com)