Indie-rock haven Austin, Texas, serves as the setting for this low-budget romantic comedy. Alex Hayes (Hamilton Von Watts) and his band are on the cusp of making it big, but then a crushing blow makes him question his choices in life and love. A doctor warns him that it may be difficult for him to father a child as time goes on, so Alex is ready to take the next step with his wife. Unfortunately, she's not prepared, though the band's sexy manager is ready to be a mom. As if that weren't enough confusion, Alex's bandmate Zeke has a crush of his own. McCartney's Genes features a cameo from Office Space star Ron Livingston.