Trust is a concept familiar to most. Whether we are cognizant of it or not, we experience it on a daily basis. Yet trust is quickly eroding in civic and political life. Americans’ trust in their government has reached all-time lows. The political and social consequences of this decline in trust are profound. What are the foundations of trust? What explains its apparent decline in society? Is there a way forward for rebuilding trust in our leaders and institutions? How should we study the role of trust across a diverse range of policy issues and problems? Given its complexity, trust as an object of study cannot be claimed by any single discipline. Rather than vouch for an overarching theory of trust, Living in an Age of Mistrust synthesizes existing perspectives across multiple disciplines to offer a truly comprehensive examination of this concept and a topic of research. Using an analytical framework that encompasses rational and cultural (or sociological) dimensions of trust, the contributions found therein provide a wide range of policy issues both domestic and international to explore the apparent decline in trust, its impact on social and political life, and efforts to rebuild trust.