This issue of Surgical Clinics of North America focuses on Issues in Transplant Surgery, and is edited by Dr. Juan Palma-Vargas. Articles will include: Kidney transplantation: Patient selection, perioperative surgical issues and expected outcomes; Kidney paired donation; Management of abdominal surgical emergencies in transplant recipients: What a general surgeon should know; Post transplant malignancy; Liver transplantation: Patient selection, perioperative surgical issues and expected outcomes; Organ Preservation 101; Pediatric Abdominal Organ Transplantation; Pancreas Transplantation; Small Bowel Transplantation; Supply vs demand: Status of organ donation in the US, the wait list, and what can be done to close the gap; and more!