Fundamentals of Information Systems Security, Fifth Edition, provides a fully updated, industry-aligned foundation in cybersecurity, preparing learners to understand, secure, and defend modern information systems. The text reinforces core concepts such as confidentiality, integrity, and availability while examining how emerging technologies and AI are reshaping today’s threat landscape. Each chapter moves from foundational principles to real-world implementation, with AI-driven scenarios integrated throughout to reflect current industry needs. The Fifth Edition supports foundational cybersecurity education and credential-focused training with alignment to CompTIA Security+, and additional mapping across CAE-CD Knowledge Unit s, CSEC 2020, and NICE Framework v2.0.0 updates. From two- and four-year colleges to technical and certificate programs, instructors can rely on this comprehensive resource to strengthen practical competencies and build real-world readiness from day one. Features and Benefits Integrates AI-related risks and threats across foundational cybersecurity principles to reflect today’s threat landscape. Features clearly defined learning objectives and structured chapters to support outcomes-based course design. Aligns with cybersecurity, IT, and AI-related curricula across two-year, four-year, graduate, and workforce programs. Addresses responsible AI use and academic integrity with reflection prompts and instructional support for educators. Maps to CompTIA Security+, CAE-CD Knowledge Unit s, CSEC 2020, and NICE v2.0.0 to support curriculum alignment. Re-designed scenario-based Cloud Lab s that reinforce concepts through real-world, hands-on virtual practice. Instructor resources include slides, test bank, sample syllabi, instructor manual, and time-on-task documentation.