This edited volume compiles a series of chapters written by experts of isotopic analysis in order to highlight the utility of various isotope systems in the reconstruction of past human behaviors. Rather than grouping contributions by specific isotopes or analytical techniques, as many isotope review articles are arranged, the volume organizes chapters by broadly defined themes of archaeological research. These include: paleodiet and life histories, human-animal interactions, and migration and mobility. In this sense, the book is arranged with the intent of being as much question based as method based. Chapters under these themes provide background information on the principles of the techniques and on the theoretical underpinnings of the research; yet they are written with the non-specialist in mind and attempt to convey these ideas clearly and succinctly. In addition to the case studies and reviews, three chapters provide greater context to the field of isotopicarchaeology, discussing its history, basic principles, and future potential. The volume aims to serve as a reference source for students and practicing archaeologists seeking to apply isotopic studies to their own research projects or to act as a reader for courses in archaeological science. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.