Far from their respective hometowns, Frieda Moss's and Sean Davis' paths cross in a very peculiar place. Street-wise and world-weary, they find themselves confused by each other's secretiveness and distracted by an unwanted attraction. Their disruptive presence is no match, though, for the seductive influence of a strange and guarded health-resort/clinic, Center for Chronic Disorders, and its eccentric Doctor Burke. A love story within a love story, The Placebo Club explores the powerful influence of believing beyond a doubt.