Est. 1973 95% Polyphenols Herbal Support Dietary Supplement Non Gmo Project Verified Lab Verified Nutrition A Brighter Way Since 1973, we've scoured the globe for the highest quality ingredients, connecting you with the most efficacious supplements that help you live brighter and embrace the moments that matter most. Discussion : Grapes have a long history of use as both a food and a medicine dating back over 6,000 years to the ancient civilizations of Greece and Egypt. Grape seeds are known to contain high concentrations of polyphenol antioxidants called Opc's (oligomeric proanthocyanidin complexes). Research suggests that Opc's may provide nutritive support for healthy cardiovascular function and capillary integrity.