Seven billionaires ban together to lease a deserted Brazilian island. After upgrading the island's infrastructure with roads, water, electricity provided by solar panels, and a tunnel through the side of a dormant volcano to build their headquarters on the crater floor, their plan is to populate the island with fourteen of the world's deadliest land predators. With very little game to survive on, it is expected that the predators will turn on each other and it will be a fight the finish with the survivor earning the title of "The Deadliest Predator." The action with be viewed on television in their headquarters with the cameras on fourteen drones, each tracking one of the predators through a microchip in the napes of the predators' necks. The drones are to be controlled by a powerful artificial intelligence computer named Horus. However, two nights before the predator's arrival a force of mercenaries hired by one of the billionaires invades the island taking control and a fifteenth predator is added to the game. But this predator is a naked unarmed man. The only way that the billionaires can regain control of the island and their program is left in the "hands" of Horus. But what can a computer and a naked man do against an armed force of thirty?