This book constitutes the refereed proceedings of the 14th International Conference on Optimization and Applications, OPTIMA 2023, held in Petrovac, Montenegro, during September 18–22, 2023. The 27 full papers included in this book were carefully reviewed and selected from 68 submissions. They were organized in topical sections as follows: ​mathematical programming; global optimization; discrete and combinatorial optimization; game theory and mathematical economics; optimization in economics and finance; and applications.