Religious sisters have created educational and healthcare systems over the past two hundred years that have transformed the Catholic community in the United States. Through their ministry, sisters have served waves of immigrants and those pushed to the margins. The growing cultural diversity of newer sisters and the diminishing number of older sisters, therefore, is both a challenge and a creative moment to be critically examined.This book examines these changes in culture and ethnicity among sisters, the structural impact of diminishing numbers, and the creative response to this new reality for religious life in the United States. In it, sisters from a variety of generations, cultures, and institutes join with the Center for Applied Research in the Apostolate (CARA) researchers to examine and reflect on CARA's recent research findings and their impact on the life and ministry of sisters today.