Minimally invasive procedures are increasingly utilized and are replacing open surgery to reduce scarring and pain, enhance patient recovery, and minimize cost. This guide provides step-by-step guidance, expert instruction, and detailed illustration of the most recent minimally invasive orthopedic spine procedures. With a variety of chapters covering critical developments in the field including the utilization of biologic materials, image-guided surgery, and bone fusion, this guide delves into discussions of indications, methods for preoperative planning, complication avoidance strategies, and patient outcomes.