More than two decades ago, a commission of 17 MIT scientists and economists released a report, Made in America, which opened with the memorable phrase, "To live well, a nation must produce well." Is that still true? Or can the United States remain a preeminent nation while other countries increasingly make the products that once were made in America? These questions were at the center of a forum titled "Making Things: 21st Century Manufacturing and Design" held during the 2011 Annual Meeting of the National Academy of Engineering. In a wide-ranging and provocative conversation, seven leaders of business, government, and academia explored the many facets of manufacturing and design and outlined the many opportunities and responsibilities posed by manufacturing for the engineering profession. Making Things: 21st Century Manufacturing and Design summarizes the discussions that took place during the 2011 forum. The report concludes with a forum agenda and each attendee's bibliography.