The agencies within the U.S. Intelligence Community (IC) depend on advanced technology to achieve their goals. While AI, cloud computing, advanced sensors, and big data analytics will fundamentally change both the global threat landscape and IC tradecraft, advances from biology, chemistry, materials, quantum science, network science, social/behavioral/economic sciences, and other fields also have that potential. Maintaining awareness of advances in science and technology is more essential than ever, to avoid surprise, to inflict surprise on adversaries, and to leverage those advances for the benefit of the nation and the IC. This report explores ways in which the IC might leverage the future research and development ecosystem.