Mila Kunis, Glenn Close, and Stephen Root star in this family drama. A 31-year-old woman reconnects with her estranged mother as she struggles to recover from a debilitating heroin addiction. Their bond is tried and tested over the critical four-day period where she has to remain clean to be eligible for opioid antagonist injections. Directed by Rodrigo Garc?a; based on Washington Post writer Eli Saslow's 2016 article on drug addiction in America.