Enzyme Kinetics Drug Metabolism: Fundamentals and Applications in Bloomington, MN

This second edition further develops the principles of applying kinetic principles to drug metabolizing enzymes and transporters. Chapters are divided into six sections detailing fundamental principles of enzyme kinetics, enzyme and transporter structures, highlighting specific oxidative and conjugative drug metabolizing enzymes and drug transporters, modeling approaches for drug metabolizing enzymes and transporters, understanding of variability both experimental and interindividual (pharmacogenomic), and expanded case studies that provide real life examples of applying these principles. Written in the highly successful
Methods in Molecular Biology
series format, chapters include introductions to their respective topics, in some cases step-by-step instructions with readily reproducible laboratory prools, and tips on troubleshooting and avoiding known pitfalls with extensive cross referencing to assist in learning.
Authoritativeand fully updated,
Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications, Second Edition
serves as a practical teaching tool for novice and advanced scientists interested in the fundamental concepts.