Dominic and Lucia Divita are vampires that will do anything for their human children. The struggle to create a better life for their family began in the slums of 1960's Rome. A vampire, Ursula Orlock offered the couple a chance at immortality. This new life takes them to the disco dance floors of New York City, but there are new dangers ahead. When the Mafia threatens to use the Church to drive them out, the Divitas make a desperate move. Dominic and Lucia must confront werewolves, witches, and soldiers of God in order to protect everything they love.