John Joiner, an agoraphobic writer, has his secluded routine disturbed by the arrival of a temporary housekeeper, Maria. Together, they stumble across a plot to kill a very wealthy and powerful businessman. Things go from bad to worse when they try to intervene. Forced to battle his phobia, John and Maria find themselves on the run, unsure of whom they can trust, trying desperately to stop a murder and to stay alive.