This handbook includes current data from the American College of Chest Physicians (ACCP) guidelines on antithrombotic and thrombolytic therapy, the latest information on heparin-induced thrombocytopenia (HIT) and heparin-induced thrombocytopenia with thrombosis (HITT), and an in-depth discussion of the drugs and dosages to use in combating deep-vein thrombosis (DVT) and pulmonary embolism (PE). The handbook also offers a section on clinical pathways, which will allow physicians to develop therapeutic goals for their patients and the sequence and timing of the actions that need to occur to achieve those goals as quickly as possible.