The man, seemingly paralyzed, eventually dies, but not before letting loose a maniacal laugh. On examination, the doctor finds nothing that could have killed him, but the case is so odd that he immediately reaches out to other doctors to see if any of their patients have manifested the same symptoms. When answers start coming in, Lowell is startled to see that a number of people have been in the same boat. After compiling a list of these patients, he (along with Ricori) starts his quest to track down the source of this horrific illness hoping to find even one factor they all had in common. Just as they're starting to make some progress the illness strikes again, this time hitting very close to home.